The NIH K99-R00 program is an important program related to the transition from postdoc to faculty positions. This program also presents an unusual opportunity for evaluation since cohorts of scientists at similar career stages compete for initial K99 awards and then can transition to R00 awards and then to R01s and other awards. I have previously posted analysis including the transitions to R00 and R01 grants, gender disparity in R01 transition probabilities, differences between NIH institutes and centers, and gender differences between R0o institutions.
I am now starting to analyze the publication patterns of K99-R00 awardees. For this study, I examined the initial 2007 K99 cohort of 182 investigators, of whom 170 transitioned to R00 awards. I examined the publications of these investigators through the Advanced Search function of PubMed. In many cases, this appeared to produce a relatively comprehensive list of publications based on comparisons with websites and other sources. In other cases, there results appeared problematic due to issues of name ambiguity or a significant number of publications that do not appear in PubMed. Publication lists through the present were generated for 135 investigators.
The total number of publications for each investigator is shown below:
The number of publications ranges from less than 10 to nearly 100. In some cases for investigators with a relatively small number of publications, technical issues may have resulted in undercounting publications while in a few other cases, the investigators appear to have left academia sometime after receiving the R00 award. Of course, publication numbers have considerable limitations and no attempt has been made at this point to examine individual publications in terms of the citations or other measures.
These publications can be broken down roughly into those leading up to the K99 award and those that occurred after receiving this award. While doing this relatively precisely would require going though individual publications, I used the number of publications in 2007 or before as a surrogate:
The publications after 2007 (2008-2014) are shown below:
These correspond to publications produced during the K99 award, during the R00 award, subsequent publications, as well as some publications of results generated prior to the K99 award that were somewhat slow to be published.
The correlation between the number of publications 2007 and before and the number of post-2007 publication is shown below:
Not surprisingly, these are relatively strongly correlated with a correlation coefficient of approximately 0.6. Of course, this reflects differences in the publication patterns between fields and other factors in addition to some more calibrated measure of investigator productivity.
One additional factor that I have examined involves the meme that a publication in Science, Nature, or Cell is highly correlated with receiving a K99 award. Examination of the publication lists reveals that approximately 20% of the K99 awardees have a publication in Science, Nature, Cell or New England Journal of Medicine prior to or in 2007. In addition, approximately 40% have a publication in other relatively high profile journals such as PNAS, other Nature or Cell journals, and the Journal of Clinical Investigation.
With this list of nearly 4000 publications along with the other data that I have assembled on this cohort of investigators, much more analysis is possible and I welcome thoughts about what might be interesting.