The K99-R00 program is an NIH-wide program but, as is typical at NIH, each institute and center has considerable flexibility about the details about how the program is administrated. For example, for the two cohorts of K99 awardees that I have been examining, the number of K99 awardees ranges from 1 for the National Institute (then National Center) for Minority Health and Health Disparities (NIMHD, MD) to 54 for the National Cancer Institute (NCI, CA). The number was not simply proportional to budget size. For example, the number of K99 awards from the National Institute of Allergy and Infectious Diseases (NIAID, AI) was 13, smaller than five other institutes despite the fact that NIAID has the second largest budget at NIH. Moreover, as one would expect by chance, the fraction of women and men among K99 awardees varies from IC to IC. This may be relevant to understanding the disparity between women and men in the probability of transitioning from an R00 award to an R01 or similar award.
These data are summarized graphically below:
The size of each circle is proportional to the number of R00 awardees from each IC.
These data may be relevant to understanding the gender disparity. For example, both NIAID and the National Institute for Neurological Diseases and Stroke (NINDS, NS) have percentages of men among R00 awardees that are slightly higher than the NIH average but all of the women from these institutes who have received R00 awards have gone on to obtain R01 or equivalent (DP2) funding through the present.
Understanding the origins of the gender disparity between women and men going from a K99 award to R01 or equivalent funding is important for determining what policy adjustments should be considered.